Use and Reporting of Patient-Reported Outcomes in Trials of Palliative Radiotherapy: A Systematic Review.

ABSTRACT:

Importance

Approximately 50% of all patients with cancer have an indication for radiotherapy, and approximately 50% of radiotherapy is delivered with palliative intent, with the aim of alleviating symptoms. Symptoms are best assessed by patient-reported outcomes (PROs), yet their reliable interpretation requires adequate reporting in publications.

Objective

To investigate the use and reporting of PROs in clinical trials of palliative radiotherapy.

Evidence review

This preregistered systematic review searched PubMed/Medline, EMBASE, and the Cochrane Center Register of Controlled Trials for clinical trials of palliative radiotherapy published from 1990 to 2020. Key eligibility criteria were palliative setting, palliative radiotherapy as treatment modality, and clinical

SUBMITTER: Fabian A 

PROVIDER: S-EPMC9500555 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature