The Resemblance between Bacterial Gut Colonization in Pigs and Humans.

ABSTRACT: Thorough understanding of the initial colonization process of human intestines is important to optimize the prevention of microbiota-associated diseases, and also to further improve the current microbial therapies. In recent years, therefore, colonization of the human gut has gained renewed interest. However, due to a lack of standardization of life events that might influence this early colonization process in humans, many generally accepted insights are based on deduction and assumption. In our review, we compare knowledge on colonization in humans with research in piglets, because the intestinal tract of pigs is remarkably similar to that of humans and the early-life events are more standardized. We assess potential similarities and challenge some concepts that have been widely accepted

SUBMITTER: Van de Vliet M 

PROVIDER: S-EPMC9500663 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature