Serum Calcification Propensity Represents a Good Biomarker of Vascular Calcification: A Systematic Review.

ABSTRACT: Vascular calcification contributes to cardiovascular morbidity and mortality. A recently developed serum calcification propensity assay is based on the half-transformation time (T50) from primary calciprotein particles (CPPs) to secondary CPPs, reflecting the serum's endogenous capacity to prevent calcium phosphate precipitation. We sought to identify and review the results of all published studies since the development of the T50-test by Pasch et al. in 2012 (whether performed in vitro, in animals or in the clinic) of serum calcification propensity. To this end, we searched PubMed, Elsevier EMBASE, the Cochrane Library and Google Scholar databases from 2012 onwards. At the end of the selection process, 57 studies were analyzed with regard to the study design, sample size, characteristics

SUBMITTER: Pluquet M 

PROVIDER: S-EPMC9501050 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature