Focal Epilepsy in Individuals with Laron Syndrome.

ABSTRACT:

Objective

The aim of the study was to describe focal epilepsy in patients with Laron syndrome (LS).

Methods

Data were retrieved from medical records of a single-center cohort of 75 patients with LS.

Results

We describe for the first time 4 patients with concomitant focal epilepsy and LS. Two of them experienced episodes of status epilepticus. Electroencephalogram examination in all 4 patients showed interictal epileptiform discharges in the temporal regions. Three achieved long-term seizure freedom on antiseizure medications.

Conclusion

Patients with LS may be at risk of developing focal epilepsy, which seems to be unrelated to hypoglycemic episodes in childhood.

SUBMITTER: Goldberg L 

PROVIDER: S-EPMC9501736 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature