Association of Sinoatrial Node Radiation Dose With Atrial Fibrillation and Mortality in Patients With Lung Cancer.

ABSTRACT:

Importance

Atrial fibrillation (AF) can develop following thoracic irradiation. However, the critical cardiac substructure responsible for AF has not been properly studied.

Objective

To describe the incidence of AF in patients with lung cancer and determine predictive cardiac dosimetric parameters.

Design, setting, and participants

This retrospective cohort study was performed at a single referral center and included 239 patients diagnosed with limited-stage small cell lung cancer (SCLC) and 321 patients diagnosed with locally advanced non-small cell lung cancer (NSCLC) between August 2008 and December 2019 who were treated with definitive chemoradiotherapy.

Exposures

Radiation dose exposure to cardiac substructures, including the chambers, coronary arteries, a

SUBMITTER: Kim KH 

PROVIDER: S-EPMC9501754 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature