Psoriasis and Renal Disorders: A Large-Scale Population-Based Study in Children and Adults.

ABSTRACT:

Background

Psoriasis is a systemic disease with associated comorbidities. An association between renal diseases and psoriasis has previously been reported in adult patients, but little is known about renal diseases in pediatric patients.

Objective

To determine whether there is an association between psoriasis and renal comorbidities in adult and pediatric patients.

Methods

This cross-sectional study analyzed the database of the largest health care maintenance organization in Israel. Logistic regression was used to calculate odds ratios to compare 68,836 psoriatic patients and 68,836 controls with respect to renal comorbidities.

Results

In adults, an inverse association emerged between psoriasis and dialysis (OR, 0.69; 95% CI, 0.58-0.83) and kidney transplantati

SUBMITTER: Friedland R 

PROVIDER: S-EPMC9501764 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature