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NeoFox: annotating neoantigen candidates with neoantigen features.


ABSTRACT: The detection and prediction of true neoantigens is of great importance for the field of cancer immunotherapy. Wesearched the literature for proposed neoantigen features and integrated them into a toolbox called NEOantigen Feature toolbOX (NeoFox). NeoFox is an easy-to-use Python package that enables the annotation of neoantigen candidates with 16 neoantigen features. NeoFox is freely available as an open source Python package released under the GNU General Public License (GPL) v3 license at https://github.com/TRON-Bioinformatics/neofox. Supplementary data are available at Bioinformatics online.

SUBMITTER: Lang F 

PROVIDER: S-EPMC9502226 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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NeoFox: annotating neoantigen candidates with neoantigen features.

Lang Franziska F   Riesgo-Ferreiro Pablo P   Löwer Martin M   Sahin Ugur U   Schrörs Barbara B  

Bioinformatics (Oxford, England) 20211101 22


<h4>Summary</h4>The detection and prediction of true neoantigens is of great importance for the field of cancer immunotherapy. Wesearched the literature for proposed neoantigen features and integrated them into a toolbox called NEOantigen Feature toolbOX (NeoFox). NeoFox is an easy-to-use Python package that enables the annotation of neoantigen candidates with 16 neoantigen features.<h4>Availability and implementation</h4>NeoFox is freely available as an open source Python package released under  ...[more]

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