Risk factors associated with sickle cell retinopathy: findings from the Cooperative Study of Sickle Cell Disease.

ABSTRACT:

Background

Sickle cell retinopathy (SCR) is one of the most important ocular manifestations of sickle cell disease (SCD). This study aims to assess the prevalence of SCR in SCD, identify risk factors for its development and progression to proliferative sickle cell retinopathy (PSCR), and evaluate the potential implications of these results on clinical practice.

Methods

This research is a secondary analysis of patients diagnosed with SCD from the epidemiological, multicenter Cooperative Study of Sickle Cell Disease (CSSCD). We included all patients who completed a full ophthalmic evaluation. We identified clinical and laboratory SCD characteristics associated with SCR using multivariate logistic regression models. Proliferative sickle cell retinopathy (PSCR) was diagnosed acc

SUBMITTER: Nawaiseh M 

PROVIDER: S-EPMC9502612 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature