Diagnostic stability in individuals with autism spectrum disorder: insights from a longitudinal follow-up study.

ABSTRACT:

Background

This longitudinal study of autism symptom trajectories provides unique information that can characterize autism features and diagnostic patterns from childhood to adulthood.

Methods

Participants (n = 155) were part of a longitudinal cohort referred for possible autism where in-person assessments were completed at ages 2, 3, 5, 9, 19, and 25. Assessors were blinded to previous diagnoses. Based on adult best estimate diagnoses, participants were categorized into one of the four groups: Retained ASD, Lost ASD, Never Had ASD, or Gained ASD Diagnosis. To examine developmental changes in autism symptoms, mixed models indicated the rate of change in ADOS CSS and ADI-R scores in each diagnostic group.

Results

A subset of participants with VIQ> and <70 were assigned

SUBMITTER: Elias R 

PROVIDER: S-EPMC9502651 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature