Rose Bengal-Modified Upconverting Nanoparticles: Synthesis, Characterization, and Biological Evaluation.

ABSTRACT: High-quality upconverting NaYF₄:Yb³⁺,Er³⁺ nanoparticles (UCNPs; 26 nm in diameter) based on lanthanides were synthesized by a high-temperature coprecipitation method. The particles were modified by bisphosphonate-terminated poly(ethylene glycol) (PEG) and Rose Bengal (RB) photosensitizer. The particles were thoroughly characterized using transmission electron microscopy, dynamic light scattering, thermogravimetric analysis, FTIR, and X-ray photoelectron and upconversion luminescence spectroscopy in terms of morphology, hydrodynamic size, composition, and energy transfer to the photosensitizer. Moreover, the singlet oxygen generation from RB-containing UCNPs was investigated using 9,10-diphenylanthracene probe under 980 nm excitation. The cytotoxicity of UCN

SUBMITTER: Nahorniak M 

PROVIDER: S-EPMC9502678 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature