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Antarctic Marine Algae Extracts as a Potential Natural Resource to Protect Epithelial Barrier Integrity.


ABSTRACT: The intestine and skin provide crucial protection against the external environment. Strengthening the epithelial barrier function of these organs is critical for maintaining homeostasis against inflammatory stimuli. Recent studies suggest that polar marine algae are a promising bioactive resource because of their adaptation to extreme environments. To investigate the bioactive properties of polar marine algae on epithelial cells of the intestine and skin, we created extracts of the Antarctic macroalgae Himantothallus grandifolius, Plocamium cartilagineum, Phaeurus antarcticus, and Kallymenia antarctica, analyzed the compound profiles of the extracts using gas chromatography-mass spectrometry, and tested the protective activities of the extracts on human intestin

SUBMITTER: Ko SH 

PROVIDER: S-EPMC9503798 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature