The Oral Microbiome Impacts the Link between Sugar Consumption and Caries: A Preliminary Study.

ABSTRACT:

Background

The excessive and frequent intake of refined sugar leads to caries. However, the relationship between the amount of sugar intake and the risk of caries is not always consistent. Oral microbial profile and function may impact the link between them. This study aims to identify the plaque microbiota characteristics of caries subjects with low (CL) and high (CH) sugar consumption, and of caries-free subjects with low (FL) and high sugar (FH) consumption.

Methods

A total of 40 adolescents were enrolled in the study, and supragingival plaque samples were collected and subjected to metagenomic analyses. The caries status, sugar consumption, and oral-health behaviors of the subjects were recorded.

Results

The results indicate that the CL group showed a higher abund

SUBMITTER: Pang L 

PROVIDER: S-EPMC9503897 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature