Metal-Polymer Nanoconjugates Application in Cancer Imaging and Therapy.

ABSTRACT: Metallic-based nanoparticles present a unique set of physicochemical properties that support their application in different fields, such as electronics, medical diagnostics, and therapeutics. Particularly, in cancer therapy, the plasmonic resonance, magnetic behavior, X-ray attenuation, and radical oxygen species generation capacity displayed by metallic nanoparticles make them highly promising theragnostic solutions. Nevertheless, metallic-based nanoparticles are often associated with some toxicological issues, lack of colloidal stability, and establishment of off-target interactions. Therefore, researchers have been exploiting the combination of metallic nanoparticles with other materials, inorganic (e.g., silica) and/or organic (e.g., polymers). In terms of biological performance, metal

SUBMITTER: Figueiredo AQ 

PROVIDER: S-EPMC9503975 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature