Ontology highlight
ABSTRACT:
SUBMITTER: Schoning V
PROVIDER: S-EPMC9504398 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Schöning Verena V Hammann Felix F
Pharmaceutics 20220830 9
Drug interactions with other drugs are a well-known phenomenon. Similarly, however, pre-existing drug therapy can alter the course of diseases for which it has not been prescribed. We performed network analysis on drugs and their respective targets to investigate whether there are drugs or targets with protective effects in COVID-19, making them candidates for repurposing. These networks of drug-disease interactions (DDSIs) and target-disease interactions (TDSIs) revealed a greater share of pati ...[more]