Histological Validation of 11Carbon-Acetate Positron Emission Tomography/Computerized Tomography in Detecting Lymph Node Metastases in Prostate Cancer.

ABSTRACT:

Purpose

Conventional imaging cannot definitively detect nodal metastases of prostate cancer. We histologically validated C-acetate positron emission tomography/computerized tomography to identify nodal metastases, examining prostate cancer factors that influence detection rates.

Materials and methods

Patients with C-acetate avid positron emission tomography/computerized tomography imaged pelvic/retroperitoneal lymph nodes underwent high extended robotic lymphadenectomy. A standardized mapping template comprising 8 predetermined anatomical regions was dissected during lymphadenectomy, allowing for matched, region based analysis and comparison of imaging and histological data.

Results

In 25 patients a total of 2,149 lymph nodes were excised (mean 86 per patient, range 2

SUBMITTER: Rajarubendra N 

PROVIDER: S-EPMC9504582 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature