Assessment of Pharmacological Potential of Novel Exopolysaccharide Isolated from Marine Kocuria sp. Strain AG5: Broad-Spectrum Biological Investigations.

ABSTRACT: With more than 17 clinically approved Drugs and over 20 prodrugs under clinical investigations, marine bacteria are believed to have a potential supply of innovative therapeutic bioactive compounds. In the current study, Kocuria sp. strain AG5 isolated from the Red Sea was identified and characterized by biochemical and physiological analysis, and examination of a phylogenetic 16S rRNA sequences. Innovative exopolysaccharide (EPS) was separated from the AG5 isolate as a major fraction of EPS (EPSR5, 6.84 g/L^-1). The analysis of EPSR5 revealed that EPSR5 has a molecular weight (Mw) of 4.9 × 10⁴ g/mol and number average molecular weight (Mn) of 5.4 × 10⁴ g/mol and contains sulfate (25.6%) and uronic acid (21.77%). Analysis of the monosaccharide composi

SUBMITTER: Alshawwa SZ 

PROVIDER: S-EPMC9504734 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature