The Human Skin Volatolome: A Systematic Review of Untargeted Mass Spectrometry Analysis.

ABSTRACT: The analysis of volatile organic compounds (VOCs) can provide important clinical information (entirely non-invasively); however, the exact extent to which VOCs from human skin can be signatures of health and disease is unknown. This systematic review summarises the published literature concerning the methodology, application, and volatile profiles of skin VOC studies. An online literature search was conducted in accordance with the preferred reporting items for systematic reviews and meta-analysis, to identify human skin VOC studies using untargeted mass spectrometry (MS) methods. The principal outcome was chemically verified VOCs detected from the skin. Each VOC was cross-referenced using the CAS number against the Human Metabolome and KEGG databases to evaluate biological origins. A tota

SUBMITTER: Mitra A 

PROVIDER: S-EPMC9504915 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature