Unknown

Dataset Information

0

Gastrointestinal Microbiome and Multiple Health Outcomes: Umbrella Review.


ABSTRACT: In recent years, there has been growing concern about the impact of the gastrointestinal microbiome on human health outcomes. To clarify the evidence for a link between the gastrointestinal microbiome and a variety of health outcomes in humans, we conducted an all-encompassing review of meta-analyses and systematic reviews that included 195 meta-analyses containing 950 unique health outcomes. The gastrointestinal microbiome is related to mortality, gastrointestinal disease, immune and metabolic outcomes, neurological and psychiatric outcomes, maternal and infant outcomes, and other outcomes. Existing interventions for intestinal microbiota (such as probiotics, fecal microbiota transplant, etc.) are generally safe and beneficial to a variety of human health outcomes, but the quality of evidence is not high, and more detailed and well-designed randomized controlled trials are necessary.

SUBMITTER: Chang C 

PROVIDER: S-EPMC9505003 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

altmetric image

Publications

Gastrointestinal Microbiome and Multiple Health Outcomes: Umbrella Review.

Chang Chengting C   Yuan Xingzhu X   Zhang Xingxia X   Chen Xinrong X   Li Ka K  

Nutrients 20220909 18


In recent years, there has been growing concern about the impact of the gastrointestinal microbiome on human health outcomes. To clarify the evidence for a link between the gastrointestinal microbiome and a variety of health outcomes in humans, we conducted an all-encompassing review of meta-analyses and systematic reviews that included 195 meta-analyses containing 950 unique health outcomes. The gastrointestinal microbiome is related to mortality, gastrointestinal disease, immune and metabolic  ...[more]

Similar Datasets

| S-EPMC10374030 | biostudies-literature
| S-EPMC5696634 | biostudies-literature
| S-EPMC10574428 | biostudies-literature
| S-EPMC10421296 | biostudies-literature
| S-EPMC6694434 | biostudies-literature
| S-EPMC10534049 | biostudies-literature
| S-EPMC10351045 | biostudies-literature
| S-EPMC8861317 | biostudies-literature
| S-EPMC7768322 | biostudies-literature
| S-EPMC10509445 | biostudies-literature