Treatment of Metastatic Melanoma at First Diagnosis: Review of the Literature.

ABSTRACT: Metastatic melanoma (MM) is a pathological entity with a very poor prognosis that, until a few decades ago, had a low response rate to systemic treatments. Fortunately, in the last few years, new therapies for metastatic melanoma have emerged. Currently, targeted therapy and immunotherapy are the mainstays of the therapeutic arsenal available for patients with unresectable or metastatic melanoma. However, both clinical evolution and drug efficacy in melanoma patients are very different depending on the stage at which it is diagnosed. In fact, the aggressiveness of melanoma is different depending on whether it debuts directly as metastatic disease or if what occurs is a relapse after a first diagnosis at an early stage, although the biological determinants are largely unknown. Another key a

SUBMITTER: Berciano-Guerrero MA 

PROVIDER: S-EPMC9505710 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature