A Randomized Controlled Trial of Three Advanced Wound Dressings in Split-Thickness Skin Grafting Donor Sites-A Personalized Approach?

ABSTRACT:

Background

Split-thickness skin grafting (STSG) is a frequently used reconstructive technique, and its donor site represents a standardized clinical model to evaluate wound dressings. We compared hydroactive nanocellulose-based, silver-impregnated and ibuprofen-containing foam wound dressings.

Methods

A total of 46 patients scheduled for elective surgery were evaluated on the STSG donor site for wound healing (time-to-healing, Hollander Wound Evaluation Scale), pain level (Visual Analogue Scale), and handling (ease of use), as well as scar quality (Patient Scar Assessment Scale, Vancouver Scar Scale) after 3, 6 and 12 months.

Results

Almost all dressings compared equally well. We observed statistically relevant differences for pain level favoring the ibuprofen-contain

SUBMITTER: Hecker A 

PROVIDER: S-EPMC9506097 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature