Aerosol measurement identifies SARS-CoV 2 PCR positive adults compared with healthy controls.

ABSTRACT:

Background

SARS-CoV-2 is spread primarily through droplets and aerosols. Exhaled aerosols are generated in the upper airways through shear stress and in the lung periphery by 'reopening of collapsed airways'. Aerosol measuring may detect highly contagious individuals ("super spreaders or super-emitters") and discriminate between SARS-CoV-2 infected and non-infected individuals. This is the first study comparing exhaled aerosols in SARS-CoV-2 infected individuals and healthy controls.

Design

A prospective observational cohort study in 288 adults, comprising 64 patients testing positive by SARS CoV-2 PCR before enrollment, and 224 healthy adults testing negative (matched control sample) at the University Hospital Frankfurt, Germany, from February to June 2021. Study objective

SUBMITTER: Gutmann D 

PROVIDER: S-EPMC9507996 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature