The interindividual variability of multimodal brain connectivity maintains spatial heterogeneity and relates to tissue microstructure.

ABSTRACT: Humans differ from each other in a wide range of biometrics, but to what extent brain connectivity varies between individuals remains largely unknown. By combining diffusion-weighted imaging (DWI) and magnetoencephalography (MEG), this study characterizes the inter-subject variability (ISV) of multimodal brain connectivity. Structural connectivity is characterized by higher ISV in association cortices including the core multiple-demand network and lower ISV in the sensorimotor cortex. MEG ISV exhibits frequency-dependent signatures, and the extent of MEG ISV is consistent with that of structural connectivity ISV in selective macroscopic cortical clusters. Across the cortex, the ISVs of structural connectivity and beta-band MEG functional connectivity are negatively associated with cortical

SUBMITTER: Karahan E 

PROVIDER: S-EPMC9508245 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature