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Long non-coding RNAs as biomarkers and therapeutic targets for ischemic stroke.


ABSTRACT:

Background

The problem of ischemic stroke (IS) has become increasingly important in recent years, as it ranks first in the structure of disability and mortality, crowding out other vascular diseases. In this regard, the study of this pathology and the search for new therapeutic and diagnostic tools remains an urgent problem of modern medical science and practice. Long non-coding RNAs (lncRNAs)-based therapeutics and diagnostic tools offer a very attractive area of study. Therefore, this systematic review aims at summarizing current knowledge on promising lncRNAs as biomarkers and therapeutic targets for IS exploring original articles and literature reviews on in vivo, in vitro and ex vivo experiments.

Methods

The current systematic review was performed accordin

SUBMITTER: Sufianova G 

PROVIDER: S-EPMC9508273 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature