The relationship between perianal fistula activity and abdominal adipose tissue in Crohn's disease: an observational study.

ABSTRACT:

Objective

The aim of this study was to analyze the relationship between abdominal adipose tissue and perianal fistula activity in patients with Crohn's disease (CD) using cross-sectional imaging.

Methods

Patients with perianal fistulizing CD who underwent pelvic magnetic resonance imaging (MRI) and abdominal computed tomography (CT) were retrospectively enrolled. We scored the fistulas in each patient's MRI images based on Van Assche's classification. The area and density of subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) (at the third, fourth, and fifth lumbar (L3, L4, and L5) levels were measured by averaging five slices of measurements at each vertebral level in CT images, and areas were further standardized by the lumbar height² (height

SUBMITTER: Xiong Z 

PROVIDER: S-EPMC9509502 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature