Augmented renal clearance in the ICU: estimation, incidence, risk factors and consequences-a retrospective observational study.

ABSTRACT:

Background

Augmented renal clearance (ARC) remains poorly evaluated in ICU. The objective of this study is to provide a full description of ARC in ICU including prevalence, evolution profile, risk factors and outcomes.

Methods

This was a retrospective, single-center, observational study. All the patients older than 18 years admitted for the first time in Medical ICU, Bichat, University Hospital, APHP, France, between January 1, 2017, and November 31, 2020 and included into the Outcomerea database with an ICU length of stay longer than 72 h were included. Patients with chronic kidney disease were excluded. Glomerular filtration rate was estimated each day during ICU stay using the measured creatinine renal clearance (CrCl). Augmented renal clearance (ARC) was defined as a 24 

SUBMITTER: Egea A 

PROVIDER: S-EPMC9510087 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature