Lectins from plants and algae act as anti-viral against HIV, influenza and coronaviruses.

ABSTRACT:

Background

Carbohydrate-lectin interactions are extremely specific as the lectin is capable of recognising monomeric and oligomeric sugars in a reversible manner. It has been known for a long time that lectins have antibacterial, antifungal, and insecticidal activities. Recently, it has been reported that many lectins can prevent the virus growth by interacting with the viral envelop surface glycoprotein. Spike protein, which is found on the surface of some enveloped viruses, is heavily mannosylated and will have strong affinity for mannose specific lectins. According to the findings, lectins have a high binding affinity for the glycans of the SARS-CoV-2 spike glycoprotein, which contains N-glycosylation sites. As a result, various lectins are being researched and developed as anti

SUBMITTER: Naik S 

PROVIDER: S-EPMC9510388 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature