Serum Syndecan-1 levels in patients with immunoglobulin A vasculitis in children.

ABSTRACT:

Objective

The aim of this study was to evaluate the serum Syndecan-1 (SDC-1) levels in patients with immunoglobulin-A vasculitis (IgAV) in children and its relation with gastrointestinal involvements.

Methods

Sixty-eight children with IgAV and 48 healthy children were enrolled in this cross-sectional study. Clinical and related laboratory data were collected from a computerized hospital database. Serum SDC-1 was collected on admission prior to treatment.

Results

Forty-eight patients fully met the IgAV diagnostic criteria at admission (IgAV group), 20 patients with rash only and diagnosed IgAV during hospitalization (Purpura group). In IgAV group, 30 patients with gastrointestinal involvements (IgAV-GI group) and 18 patients without gastrointestinal involvements (IgAV-

SUBMITTER: Jia X 

PROVIDER: S-EPMC9510791 | biostudies-literature | 2022 Sep-Oct

REPOSITORIES: biostudies-literature