Association of the systemic immune-inflammation index with all-cause mortality in patients with arteriosclerotic cardiovascular disease

ABSTRACT:

Objective

Systemic immune-inflammation index (SII), derived from blood cell counts of circulating platelets, neutrophils, and lymphocytes, has been identified as a novel inflammatory and prognostic marker. However, the clinical value of SII in patients with arteriosclerotic cardiovascular disease (ASCVD) had not been further explored. Thus, this study is designed to explore the associations of SII with mortality in ASCVD individuals.

Methods

All individuals with ASCVD aged ≥20 years were included from the National Health and Nutritional Examination Surveys (NHANES) 2005–2014 and followed for survival until 31 December 2019. Multivariable Cox analysis investigated the associations between SII, evaluated as a continuous variable with splines, as categorical ones (quartiles)

SUBMITTER:  

PROVIDER: S-EPMC9510918 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature