Opioid-free sedation for atlantoaxial cerebrospinal fluid collection in adult horses.

ABSTRACT:

Background

Atlantoaxial (AA) cerebrospinal fluid (CSF) collection in standing horses utilizes the controlled narcotic morphine, thereby limiting feasibility in field practice settings.

Objectives

To compare AA CSF collection time and reaction scores in horses sedated with morphine-containing and opioid-free sedation protocols: detomidine + morphine (DM), detomidine + xylazine (DX), detomidine + detomidine (DD), detomidine alone (D0); To develop a novel method for assessing sedation in standing horses using open-source motion-tracking software.

Animals

Six healthy adult horses.

Methods

Randomized crossover. Atlantoaxial CSF collections were performed weekly for 4 weeks. Horses received sedation protocols in random order. Procedure time and procedure reaction sco

SUBMITTER: Cock G 

PROVIDER: S-EPMC9511061 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature