Risk Factors for Colistin-Resistant Carbapenem-Resistant Klebsiella pneumoniae in the Postacute Care Setting

ABSTRACT: Abstract We assessed risk factors for colistin resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) from 375 patients in long-term acute care hospitals. Recent colistin or polymyxin B exposure was associated with increased odds of colistin resistance (adjusted odds ratio = 1.11 per day of exposure, 95% confidence interval = 1.03–1.19, P = .007). Among patients in long-term acute care hospitals with carbapenem-resistant Klebsiella pneumoniae (CRKP) infection or colonization, recent colistin or polymyxin B exposure was associated with increased odds of colistin-resistant CRKP.

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PROVIDER: S-EPMC9511120 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature