Long-term survival outcomes of pediatric adrenal malignancies: An analysis with the upstaged SEER registry during 2000-2019.

ABSTRACT:

Objective

To investigate the clinicopathological characteristics and long-term survival outcomes of pediatric adrenal malignancies.

Method

This study retrospectively analyzed children with pathologically confirmed pediatric adrenal malignancies from Surveillance, Epidemiology, and End Results Database from 2000 to 2019. Kaplan-Meier curve was used to assess the overall survival (OS) and cancer-special survival (CSS), and the Log-Rank method was used to calculate statistical differences. Cox proportional hazards model and Fine-and-Grey model were used to calculate the hazard ratio (HR) of all-cause mortality risk and the sub-distribution HR (sHR) of disease-specific mortality risk, respectively, and their corresponding 95% confidence intervals (CI).

Results

1601 childr

SUBMITTER: Lv Z 

PROVIDER: S-EPMC9511147 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature