Characteristics of myeloproliferative neoplasm-associated portal hypertension and endoscopic management of variceal bleeding

ABSTRACT:

Background:

Myeloproliferative neoplasms (MPNs) are a rare yet important clinical cause of portal hypertension, which may cause recurrent gastroesophageal variceal bleeding (GVB). MPN-associated variceal bleeding lacks specific guidelines and clinical consensus and desiderates cohort studies. We performed a multicenter retrospective study to investigate the efficacy of endoscopic management of bleeding in MPNs.

Methods:

We included consecutive MPN patients with gastroesophageal varices in eight tertiary university hospitals between January 2007 and March 2020. The clinical characteristics of participants were summarized. MPN patients with a history of GVB were followed up for the rebleeding and death, compared with controls suffering from schistosomiasis-associated portal

SUBMITTER:  

PROVIDER: S-EPMC9511301 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature