Enhanced red blood cell distribution width to platelet ratio is a predictor of mortality in patients with sepsis: a propensity score matching analysis based on the MIMIC-IV database.

ABSTRACT:

Objective

To explore the association between dynamic changes in red blood cell distribution width to platelet count ratio (RPR) during hospitalisation and short-term mortality in patients with sepsis.

Design

A retrospective cohort study using propensity score matching.

Setting

Intensive care units (ICUs) of Beth Israel Deaconess Medical Center.

Participants

A total of 8731 adult patients with sepsis were included in the study. The patients were identified from the ICU of the Medical Information Mart for Intensive Care database. The observed group included patients who experienced an increase in RPR of more than 30% during the first week of ICU admission, whereas the control group included the rest.

Main outcome and measure

Using propensity score matching

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC9511593 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature