Protocol for systematic review and network meta-analysis of comparative effectiveness of surgical interventions for primary congenital glaucoma.

ABSTRACT:

Introduction

Primary congenital glaucoma (PCG), a type of childhood glaucoma, is primarily treated surgically to lower intraocular pressure (IOP). Failure to intervene could result in partial, or even total, blindness. Various surgical intervention types have been proposed for PCG, though the evidence on comparative effectiveness remains limited. The current protocol is an ongoing network meta-analysis enabling comparative investigation of surgical interventions for which randomised controlled trials (RCTs) are available. Our aim is to systematically compare the efficacy of various types of surgical intervention for patients with PCG.

Methods and analysis

Studies of interest will assess the effects of those surgical interventions on surgery-naïve children (age <18 years) suf

SUBMITTER: Lee YJ 

PROVIDER: S-EPMC9511603 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature