MiR-34b/c play a role in early sex differentiation of Amur sturgeon, Acipenser schrenckii

ABSTRACT:

Background

Sex differentiation can be viewed as a controlled regulatory balance between sex differentiation-related mRNAs and post-transcriptional mechanisms mediated by non-coding RNAs. In mammals, increasing evidence has been reported regarding the importance of gonad-specific microRNAs (miRNAs) in sex differentiation. Although many fishes express a large number of gonadal miRNAs, the effects of these sex-biased miRNAs on sex differentiation in teleost fish remain unknown. Previous studies have shown the exclusive and sexually dimorphic expression of miR-34b/c in the gonads of the Amur sturgeon (Acipenser schrenckii), suggesting its potential role in the sex differentiation process.

Results

Using quantitative real-time PCR (qPCR), we observed that miR-34b/c showed consi

SUBMITTER: Zhang X 

PROVIDER: S-EPMC9511750 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature