Association between Long-Term Air Pollution, Chronic Traffic Noise, and Resting-State Functional Connectivity in the 1000BRAINS Study.

ABSTRACT:

Background

Older adults show a high variability in cognitive performance that cannot be explained by aging alone. Although research has linked air pollution and noise to cognitive impairment and structural brain alterations, the potential impact of air pollution and noise on functional brain organization is unknown.

Objective

This study examined the associations between long-term air pollution and traffic noise with measures of functional brain organization in older adults. We hypothesize that exposures to high air pollution and noise levels are associated with age-like changes in functional brain organization, shown by less segregated brain networks.

Methods

Data from 574 participants (44.1% female, 56-85 years of age) in the German 1000BRAINS study (2011-2015) were

SUBMITTER: Glaubitz L 

PROVIDER: S-EPMC9512146 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature