Inadvertent QRS prolongation by an optimization device-based algorithm in patients with cardiac resynchronization therapy.

ABSTRACT:

Background

Device-based algorithms offer the potential for automated optimization of cardiac resynchronization therapy (CRT), but the process for accepting them into clinical use is currently still ad-hoc, rather than based on pre-clinical and clinical testing of specific features of validity. We investigated how the QuickOpt-guided VV delay (VVD) programming performs against the clinical and engineering heuristic of QRS complex shortening by CRT.

Methods

A prospective, 2-center study enrolled 37 consecutive patients with CRT. QRS complex duration (QRSd) was assessed during intrinsic atrioventricular conduction, synchronous biventricular pacing, and biventricular pacing with QuickOpt-proposed VVD. The measurements were done manually by electronic calipers in signal-averaged

SUBMITTER: Sedlacek K 

PROVIDER: S-EPMC9512171 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature