Comparing the long non-coding RNA expression profiles of skeletal muscle and kidney tissues from patients with diabetes.

ABSTRACT:

Background

Diabetes causes the dysregulation of several organs, and these effects are often closely associated with changes in the expression of long non-coding RNAs (lncRNAs), a group of non-coding RNAs, within these tissues. Previous studies have described a variety of changes in the expression profile of several lncRNAs from different organs in response to the pathogenesis of diabetes. However, none of these studies compared the expression profiles of these lncRNAs between these organs. This study was designed to identify common and specific lncRNAs involved in the progression of diabetes in the skeletal muscles and kidneys.

Methods

Publicly available RNA sequencing data of diabetic patients was obtained from the Gene Expression Omnibus database. By analyzing the expressi

SUBMITTER: Kim YK 

PROVIDER: S-EPMC9512191 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature