Association between predialysis creatinine and mortality in acute kidney injury patients requiring dialysis.

ABSTRACT:

Background

Creatinine is widely used to estimate renal function, but this is not practical in critical illness. Low creatinine has been associated with mortality in many clinical settings. However, the associations between predialysis creatinine level, Sepsis-related Organ Failure Assessment (SOFA) score, fluid overload, and mortality in acute kidney injury patients receiving dialysis therapy (AKI-D) has not been fully addressed.

Methods

We extracted data for AKI-D patients in the eICU and MIMIC databases. We conducted a retrospective observational cohort study using the eICU dataset. The study cohort was divided into the high-creatine group and the low-creatinine group by the median value (4 mg/dL). The baseline patient information included demographic data, laboratory test

SUBMITTER: Chang HH 

PROVIDER: S-EPMC9512211 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature