Confounding factors in the assessment of oral mucositis in head and neck cancer.

ABSTRACT: Treatment of locally advanced head and neck carcinoma not amenable for surgical resection or resected with high-risk features is usually based on (chemo-)radiation treatment. Oral mucositis represents one of the main side effects of (chemo-)radiation, with an important impact on quality of life and causing approximately 20% of early interruption of treatment, leading to a suboptimal dose administered. Treatment and prevention of oral mucositis have a central role in the therapeutic pathways of head and neck cancer patients but remains quite challenging. Although extensive research is conducted to identify interventions for the management of mucositis, very few interventions had sufficient evidence to generate an international expert consensus. This may be partially explained by confounding

SUBMITTER: Lorini L 

PROVIDER: S-EPMC9512735 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature