ADRB2 expression predicts the clinical outcomes and is associated with immune cells infiltration in lung adenocarcinoma.
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ABSTRACT:
SUBMITTER: Ji L
PROVIDER: S-EPMC9512930 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
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ADRB2 expression predicts the clinical outcomes and is associated with immune cells infiltration in lung adenocarcinoma.
Ji Lingyun L Xu Fei F Zhang Jingtao J Song Ting T Chen Weida W Yin Xi X Wang Qingqing Q Chen Xiubao X Li Xin X Guo Minghao M Chen Zetao Z
Scientific reports 20220926 1
The gene encoding beta2-adrenergic receptor (β2-AR), adrenoceptor beta 2 (ADRB2), has been reported to closely associated with various cancers. However, its role in lung adenocarcinoma (LUAD) remains controversial. This research shed light on the prognostic value of ADRB2 in LUAD and further explored its association with immune cell infiltration. ADRB2 was significantly decreased in LUAD. ADRB2 expression in LUAD was significantly correlated with gender, smoking status, T classification, and pat ...[more]
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