Early surgery vs conservative management among asymptomatic aortic stenosis: A systematic review and meta-analysis

ABSTRACT: Highlights • Aortic valve replacement remains the definitive choice of treatment for AS.• All-cause mortality and adverse events are lower with early surgical valve repair.• In high-risk AS patients, early surgery is safer than conservative management.• Early intervention is crucial to prevent irreversible damage of AS.

Introduction

Although aortic valve replacement in severe symptomatic Aortic Stenosis (AS) are clearly outlined, the role of surgical intervention in asymptomatic severe AS remains unclear with limited evidence. The aim of our meta-analysis is to evaluate the efficacy and safety of early surgical aortic valve repair compared to conservative management.

Methods

A systematic literature search was performed in PubMed, Scopus, Embase and Cochrane databases for

SUBMITTER: Jaiswal V 

PROVIDER: S-EPMC9513172 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature