Bladder preservation: Translating discovery for clinical impact in urothelial cancer.
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ABSTRACT:
SUBMITTER: Miyamoto DT
PROVIDER: S-EPMC9513532 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Publications
Bladder preservation: Translating discovery for clinical impact in urothelial cancer.
Miyamoto David T DT Abbosh Philip H PH West Catharine M L CML Mouw Kent W KW
Urologic oncology 20201128 4
Muscle-invasive bladder cancer can be treated with either radical cystectomy or bladder preservation approaches, and there is a need for reliable biomarkers to guide the optimal choice of therapy. The recent elucidation of the genomic landscape and biological drivers of bladder cancer has enabled the identification of tumor molecular features that may be helpful in driving clinical decision-making. Here, we summarize recent efforts to develop molecular biomarkers that could be leveraged to guide ...[more]
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