Successful conversion therapy for unresectable hepatocellular carcinoma is getting closer: A systematic review and meta-analysis

ABSTRACT:

Background

Conversion therapy provides selected patients with unresectable hepatocellular carcinoma the opportunity to undergo a curative hepatectomy and achieve long-term survival. Although various regimens have been used for conversion therapy, their conversion rate and safety remain uncertain. Therefore, we conducted some meta-analyses to evaluate the efficacy and safety of several conversion regimens in order to elucidate the optimal regimen.

Method

We performed systematic literature research on PubMed, Embase, and the Web of Science until July 30, 2022. Chemotherapy, transcatheter arterial chemoembolization (TACE), molecular therapy (targeted therapy, immunotherapy, or a combination of both), and combined locoregional-systemic therapy were the conversion regimens we

SUBMITTER:  

PROVIDER: S-EPMC9513549 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature