Lutetium background radiation in total-body PET-A simulation study on opportunities and challenges in PET attenuation correction.

ABSTRACT: The current generation of total-body positron emission tomography (PET) scanners offer significant sensitivity increase with an extended axial imaging extent. With the large volume of lutetium-based scintillation crystals that are used as detector elements in these scanners, there is an increased flux of background radiation originating from ¹⁷⁶Lu decay in the crystals and higher sensitivity for detecting it. Combined with the ability of scanning the entire body in a single bed position, this allows more effective utilization of the lutetium background as a transmission source for estimating 511 keV attenuation coefficients. In this study, utilization of the lutetium background radiation for attenuation correction in total-body PET was studied using Monte Carlo simulations of a

SUBMITTER: Omidvari N 

PROVIDER: S-EPMC9513593 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature