A Metascore of Multiple Imaging Methods to Measure Long-Term Glaucoma Structural Progression.

ABSTRACT:

Purpose

To develop a structural metascore (SMS) that combines measurements from different devices and expresses them on a single scale to facilitate their long-term analysis.

Methods

Three structural measurements (Heidelberg Retina Tomograph II [HRT] rim area, HD-Cirrus optical coherence tomography [OCT] average retinal nerve fiber layer [RNFL] thickness, Spectralis OCT RNFL global thickness) were normalized on a scale of 0 to 100 and converted to a reference value. The resultant metascores were plotted against time. SMS performance was evaluated to predict future values (internal validation), and correlations between the average grades assigned by three clinicians were compared with the SMS slopes (external validation).

Results

The linear regression fit with the vari

SUBMITTER: De Gainza A 

PROVIDER: S-EPMC9513740 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature