Cationic Covalent Organic Polymer Thin Film for Label-free Electrochemical Bacterial Cell Detection.

ABSTRACT: Numerous species of bacteria pose a serious threat to human health and cause several million deaths annually. It is therefore essential to have quick, efficient, and easily operable methods of bacterial cell detection. Herein, we synthesize a novel cationic covalent organic polymer (COP) named CATN through the Menshutkin reaction and evaluate its potential as an impedance sensor for Escherichia coli cells. On account of its positive surface charge (ζ-potential = +21.0 mV) and pyridinium moieties, CATN is expected to interact favorably with bacteria that possess a negatively charged cell surface through electrostatic interactions. The interdigitated electrode arrays were coated with CATN using a simple yet non-traditional method of electrophoresis and then used i

SUBMITTER: Skorjanc T 

PROVIDER: S-EPMC9513792 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature