Environmental and maternal factors shaping tonsillar microbiota development in piglets.

ABSTRACT:

Background

The palatine tonsils are part of the mucosal immune system and stimulate immune responses through M cell uptake sampling of antigens and bacteria in the tonsillar crypts. Little is known about the development of the tonsillar microbiota and the factors determining the establishment and proliferation of disease-associated bacteria such as Streptococcus suis. In this study, we assessed tonsillar microbiota development in piglets during the first 5 weeks of life and identified the relative importance of maternal and environmental farm parameters influencing the tonsillar microbiota at different ages. Additionally, we studied the effect sow vaccination with a bacterin against S. suis on microbiota development and S. suis colonisation in their offspring.

Results

Amplic

SUBMITTER: Fredriksen S 

PROVIDER: S-EPMC9513891 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature