Efficient compartmentalization in insect bacteriomes protects symbiotic bacteria from host immune system.

ABSTRACT:

Background

Many insects house symbiotic intracellular bacteria (endosymbionts) that provide them with essential nutrients, thus promoting the usage of nutrient-poor habitats. Endosymbiont seclusion within host specialized cells, called bacteriocytes, often organized in a dedicated organ, the bacteriome, is crucial in protecting them from host immune defenses while avoiding chronic host immune activation. Previous evidence obtained in the cereal weevil Sitophilus oryzae has shown that bacteriome immunity is activated against invading pathogens, suggesting endosymbionts might be targeted and impacted by immune effectors during an immune challenge. To pinpoint any molecular determinants associated with such challenges, we conducted a dual transcriptomic analysis of S. oryzae's bacteri

SUBMITTER: Ferrarini MG 

PROVIDER: S-EPMC9513942 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature