Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs.

ABSTRACT:

Introduction

Porcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs.

Methods

To investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan (2/44), Manitoba (2/44), Quebec (4/44), Alberta (11/44) and Ontario (25/44) submitted to diagnostic laboratories in Canada between 2019 and 2021 were sequenced and analyzed.

Results

Phylogenetic analysis of capsid genes showed that all of the 44 Canadian strains classified into PCV3a and segregated into seven lineages with common amino acid changes observed at A24V, R27K, N56D, T77S, Q98R, L150I (F) and R168K positions.

Conclusion

Future studies are required to determine whether the polymorphisms in capsid proteins, a

SUBMITTER: Zhang M 

PROVIDER: S-EPMC9514502 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature